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pentobarbital will reduce the level or effect of diazepam buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor. Sturdy or average CYP3A4 inducers may maximize price of diazepam elimination; hence, efficacy of diazepam might be diminished.pentobarbital will decrease the level or outcome of atorvastatin by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Coadministration of zuranolone with other CNS depressants might boost impairment of psychomotor efficiency or CNS depressant results. If unavoidable, take into consideration dose reduction. .
pentobarbital will reduce the extent or result of artemether/lumefantrine by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Coadministration with strong CYP3A4 inducers can lead to lessened serum concentrations and loss of antimalarial efficacy
pentobarbital will lower the extent or outcome of sunitinib by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe.
Induction of microsomal enzymes by this drug, may well shorten the half-life of doxycycline for so long as 2 months following barbiturate therapy discontinued; monitor medical response to doxycycline intently if equally medicine administered concurrently
pentobarbital will lower the extent or result of midostaurin by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Stay away from or Use Alternate Drug. Robust CYP3A4 inducers may possibly decrease midostaurin concentrations resulting in reduced efficacy.
Untimely infants are significantly liable to the depressant effects of barbiturates; if barbiturates are used for the duration of labor and shipping and delivery, resuscitation machines must click here be offered
pentobarbital will minimize the extent or outcome of ethinylestradiol by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Prevent or Use Alternate Drug. The efficacy of hormonal contraceptives could be diminished. Usage of a nonhormonal contraceptive is usually recommended.
pentobarbital will reduce the extent or outcome of naloxegol by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Utilization of naloxegol with powerful CYP3A4 inducers will not be encouraged
pentobarbital will decrease the extent or effect of tamoxifen by impacting hepatic enzyme CYP2C9/ten metabolism. Use Caution/Keep track of.
pentobarbital will minimize the level or effect of zonisamide by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Unfamiliar.
pentobarbital will lower the extent or result of armodafinil by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Small/Importance Not known.
pentobarbital will reduce the extent or effect of estropipate by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Observe.